Comparison of Vaginal Versus Sublingual Misoprostol in the Treatment of First Trimester Missed Miscarriage

• Status: Recruiting
• Trial end date: 2021-04-01
• Target enrollment: 0
• Participant gender: Female

Summary

The miscarriage is one of the adverse outcomes of pregnancy and is responsible for stress and anxiety of the couple. there are different types of miscarriages.missed miscarriage also known as early fetal demise is one of the type of miscarriage in which patient is mostly asymptomatic but Ultrasound shows absent fetal cardiac activity.Traditionally surgical evacuation of uterus was the treatment of choice for miscarriage.The treatment of miscarriage has evolved significantly in recent years.medical management using misoprostol is the newest treatment option.Misoprostol is a synthetic prostaglandin E(1) analogue that is commonly used for medical miscarriage It can be given orally, vaginally and sublingually.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Islamabad Medical and Dental College
• Treatments: Alprostadil; Misoprostol

Criteria

Inclusion Criteria:

• Confirmed diagnosis of missed miscarriage on pelvic ultrasound

• Gestational age ≤ 13 weeks

Exclusion Criteria:

• Patients who opted for surgical or expectant management.

• Patients with co-morbidity