Overview

Comparison of Voice Therapy and Antireflex Therapy in LPR

Status:
Withdrawn
Trial end date:
2018-01-01
Target enrollment:
Participant gender:
Summary
This study will be a prospective, randomized, unblinded but controlled trial. Patients presenting to the Otolaryngology clinic who are diagnosed with laryngopharyngeal reflux disorder related dysphonia and meet inclusion criteria will be eligible to enroll in the study. Subjects will be randomized to one of three treatment arms, voice therapy, anti-reflux therapy, or a combination of voice therapy and anti-reflux therapy. Reflux symptom index (RSI) scores, reflux finding scores (RFS), voice handicap index-10 (VHI-10) scores, and consensus auditory perceptual evaluation-voice (CAPE-V) scores will be compared prior to initiation of therapy as well as at 1, 2, and 3 months following initiation of treatment.
Phase:
Phase 4
Details
Lead Sponsor:
Temple University
Treatments:
Dexlansoprazole
Esomeprazole
Lansoprazole
Omeprazole