Comparison of Vonoprazan-based Dual and Triple Therapies for H. Pylori Eradication
Status:
Completed
Trial end date:
2019-03-31
Target enrollment:
Participant gender:
Summary
Patients infected with H. pylori were randomly assigned to the dual therapy with vonoprazan
20 mg bid and amoxicillin 500 mg tid for 1 week or the triple therapy with vonoprazan 20 mg
bid, amoxicillin 750 mg bid and clarithromycin 200 mg or metronidazole 250 mg bid bid for 1
week. Success or failure of eradication was determined by the 13C-urea breath test performed
at 1 month after the therapy.