Comparison of the Analgesic Effects of Dronabinol and Smoked Marijuana in Daily Marijuana Smokers
Status:
Completed
Trial end date:
2013-05-01
Target enrollment:
Participant gender:
Summary
The following study is designed to determine the analgesic efficacy of smoked marijuana (0,
1.98, and 3.56% THC) and oral THC (0, 10, and 20 mg) in the Cold-Pressor Test (CPT), a
laboratory model of pain which has predictive validity for clinical use of analgesics. Oral
THC (dronabinol) is known to have a slower onset and longer duration of action compared with
smoked marijuana. Therefore, the analgesic effects of oral THC is expected to peak later and
last longer than effects produced by smoked marijuana.
Phase:
Phase 2
Details
Lead Sponsor:
New York State Psychiatric Institute
Collaborators:
National Institute on Drug Abuse (NIDA) Research Foundation for Mental Hygiene, Inc.