Comparison of the Antihypertensive Efficacy of Valsartan and Enalapril After Missing One Dose
Status:
Completed
Trial end date:
2007-03-01
Target enrollment:
Participant gender:
Summary
This study was designed in order to evaluate the blood pressure lowering effect of valsartan
compared to enalapril over 24 hours after skipping one daily dose. Both drugs act on the
renin-angiotensin-aldosterone system (RAAS) and are widely use for the treatment of
hypertension. Previous studies had a significant limitation: the effect of a missing dose was
not evaluated after the whole 24 hours post missing dose period (48 hours after last taken
dose), and as a result, it does not imitate the real life situation of a missing dose.
Phase:
Phase 4
Details
Lead Sponsor:
University of Vigo
Collaborators:
Hospital Clinico Universitario de Santiago Novartis