Comparison of the Clinical Efficacy of Naproxen, Associated or Not With Esomeprazol, in Lower Third Molar Removal
Status:
Completed
Trial end date:
2016-03-01
Target enrollment:
Participant gender:
Summary
The present clinical trial randomized compared the clinical efficacy of the naproxen
associated or not with esomeprazol, for the removal of lower third molars. Onset, duration of
postoperative analgesia, duration of anesthetic action on soft tissues, intraoperative
bleeding, hemodynamic parameters, postoperative mouth opening and wound healing at the 7th
postoperative day were evaluated. For this purpose, 50 healthy volunteers underwent removal
of symmetrically positioned lower third molars, in two separate appointments (one to two
months apart), under local anesthesia with either articaine 4% (1:200,000 adrenaline) in a
doubleblind, randomized and crossed manner.
Phase:
Phase 4
Details
Lead Sponsor:
Giovana Maria Weckwerth
Collaborator:
Fundação de Amparo à Pesquisa do Estado de São Paulo