Comparison of the Cosmetic Effects of Bakuchiol and Retinol

• Status: Completed
• Trial end date: 2019-03-01
• Target enrollment: 0
• Participant gender: All

Summary

Subjects will be assigned to a retinoid cream or bakuchiol to compare the cosmetic effects. This will take place over a 12 week period.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of California, Davis
• Treatments: Retinol palmitate; Vitamin A

Criteria

Inclusion Criteria:

• Individuals aged 30-55

Exclusion Criteria:

• Adults unable to consent

• Individuals who are not yet adults (infants, children, teenagers)

• Pregnant or breast feeding women

• Prisoners

• Those with acne, eczema, seborrheic dermatitis, rosacea or polycystic ovarian syndrome

• Those who have used isotretinoin in the last 6 months

• Those who have used products containing salicylic acid, beta hydroxyl acids or vitamins A, C, or E in the last 14 days

• Those who have used topical antibiotics or topical retinoids in the last 30 days

• Those who are currently smoking or have smoked within the past 3 years.

• Those who have had a recent surgical or cosmetic procedure in the last 3 months that can affect facial wrinkles or facial hyperpigmentation, such as botulinum toxin injections, chemical peels, laser based therapies to the face, or face lift surgeries