Comparison of the Effects for Lightening the Shiners Among Different Treatments for Rhinitis

• Status: Recruiting
• Trial end date: 2032-03-31
• Target enrollment: 0
• Participant gender: All

Summary

Background: Shiners are caused when blood and other fluids accumulate in the infraorbital groove. It develops resulting from lots of problems. In patient with rhinitis, either allergic rhinitis or non-allergic rhinitis, shiners are believed to be caused by venous stasis resulting from nasal congestion. This study is aiming that comparison of the effectiveness of treatment of rhinitis (either allergic rhinitis or non-allergic rhinitis) to lighten not only the rhinitis but also the shiners. Randomized control studies.

Design: The investigators will recruit children (6-12 y/0), adolescent (13-18 y/o), or adults (19-65 y/o) with either allergic rhinitis or non-allergic rhinitis, and patients will be randomly assigned to groups (oral antihistamine, combined nasal corticosteroids with oral antihistamine, combined nasal corticosteroids with oral antihistamine plus nasal decongestant, combined nasal corticosteroids with oral antihistamine plus nasal irrigation, combined oral antihistamine with nasal irrigation, or nasal antihistamine only). Digital image will be recorded and analyzed to compare the change of shiners between before and after treatment for rhinitis. The clinical data were collected including patient's data, history, laboratory data, Pediatric Rhinoconjunctivitis Quality of Life Questionnaire (PRQLQ), Adolescent Rhinoconjunctivitis Quality of Life Questionnaire (AdolRQLQ), or mini Rhinoconjunctivitis Quality of Life Questionnaire (mini-RQLQ), and medications. The primary outcome is to answer whether the levels of shiners can be alleviated by using therapies in patient with rhinitis. And the secondary outcome is to figure out which therapies work most effectively.

Keywords: allergic rhinitis, vasomotor rhinitis, shiners, nasal corticosteroids

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Camillians Saint Mary's Hospital Luodong
• Treatments: Cetirizine; Levocetirizine; Mometasone Furoate; Oxymetazoline; Phenylephrine

Criteria

Inclusion Criteria:

• Clinical diagnosis of moderate to severe rhinitis, either allergic rhinitis or non-allergic rhinitis.

Exclusion Criteria:

• Chronic rhinosinusitis

• Trauma to the forehead or nose

• Face surgery

• Malignancy

• Pregnancy

• Respiratory tract infections within a week before beginning the study

• Usage of medications for rhinitis within a week before beginning the study