Comparison of the Effects for Lightening the Shiners Among Different Treatments for Rhinitis
Status:
Recruiting
Trial end date:
2032-03-31
Target enrollment:
Participant gender:
Summary
Background: Shiners are caused when blood and other fluids accumulate in the infraorbital
groove. It develops resulting from lots of problems. In patient with rhinitis, either
allergic rhinitis or non-allergic rhinitis, shiners are believed to be caused by venous
stasis resulting from nasal congestion. This study is aiming that comparison of the
effectiveness of treatment of rhinitis (either allergic rhinitis or non-allergic rhinitis) to
lighten not only the rhinitis but also the shiners. Randomized control studies.
Design: The investigators will recruit children (6-12 y/0), adolescent (13-18 y/o), or adults
(19-65 y/o) with either allergic rhinitis or non-allergic rhinitis, and patients will be
randomly assigned to groups (oral antihistamine, combined nasal corticosteroids with oral
antihistamine, combined nasal corticosteroids with oral antihistamine plus nasal
decongestant, combined nasal corticosteroids with oral antihistamine plus nasal irrigation,
combined oral antihistamine with nasal irrigation, or nasal antihistamine only). Digital
image will be recorded and analyzed to compare the change of shiners between before and after
treatment for rhinitis. The clinical data were collected including patient's data, history,
laboratory data, Pediatric Rhinoconjunctivitis Quality of Life Questionnaire (PRQLQ),
Adolescent Rhinoconjunctivitis Quality of Life Questionnaire (AdolRQLQ), or mini
Rhinoconjunctivitis Quality of Life Questionnaire (mini-RQLQ), and medications. The primary
outcome is to answer whether the levels of shiners can be alleviated by using therapies in
patient with rhinitis. And the secondary outcome is to figure out which therapies work most
effectively.
Keywords: allergic rhinitis, vasomotor rhinitis, shiners, nasal corticosteroids