Comparison of the Effects of Remifentanil and Dexmedetomidine Administered Under General Anesthesia in Rhinoplasty
Status:
Completed
Trial end date:
2022-07-31
Target enrollment:
Participant gender:
Summary
The investigators compared the effects of remifentanil and dexmedetomidine administered under
general anesthesia on hemodynamics, postoperative pain, recovery, postoperative nausea,
vomiting, shivering, patient's and surgeon's satisfaction in patients undergoing elective
rhinoplasty. A single-center, prospective, blinded, randomized controlled trial. After the
approval of the hospital ethics committee (KA22/12), fifty volunteers aged 18-65 years who
underwent rhinoplasty under elective conditions accepted the study in the American Society of
Anesthesiologists (ASA) I-III class. The patients were randomly divided into the remifentanil
group (group R) and the dexmedetomidine group (group D). Group R (n=25) was initially to
receive remifentanil 0.01-0.2 g/kg/min without intraoperative loading. Group D (n=25)
dexmedetomidine, was initiated with a bolus of 1 mg/kg and received 0.2-0.7 g/kg per hour as
an infusion during surgery.