Comparison of the Efficacy of Topical Ibuprofen to Oral Ibuprofen in Adolescent Athletes

• Status: Terminated
• Trial end date: 2009-04-01
• Target enrollment: 0
• Participant gender: All

Summary

This study was made to compare the efficacy of topical ibuprofen in gel form with oral ibuprofen in the treatment of sub-acute soft tissue injuries while comparing the tolerability of the delivery methods

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Akron Children's Hospital
• Treatments: Ibuprofen

Criteria

Inclusion Criteria:

• Age 12-19yo

• soft tissue injury or flare up of soft tissue injury within 10 days to 8 weeks

Exclusion Criteria:

• Known hypersensitivity to aspirin or any NSAID,

• allergy to eggs or egg products

• history of asthma, renal disease, GI disease, active or suspected bleeding peptic ulcer (past or present), anemia, hypertension, other systemic disease significantly affecting liver or renal function

• serious injury within six months

• currently on anticoagulants

• pregnant or lactating females

• active arthritis in affected limb

• open wounds, infected skin or fractures

• opioid use within 7 days

• severe psychological disorder

• prior topical medication applied to the painful region/area of study