Composite Variability Index Versus Bispectral Index (BIS)

• Status: Completed
• Trial end date: 2010-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to compare the accuracy of the changes in CVI in response to a standardized noxious stimulus during various targeted pseudo-steady-state concentrations of remifentanil and various steady state level of BIS as guided by propofol effect compartment controlled TCI (closed-loop).

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Medical Center Groningen
• Treatments: Propofol; Remifentanil

Criteria

Inclusion Criteria:

• ASA class I and II patients requiring general anesthesia for elective surgical procedures

Exclusion Criteria:

• patient refusal

• weight less than 70% or more than 130% of ideal body weight,

• neurological disorder

• recent use of psycho-active medication, including alcohol.