Compound Herbal Formula (TPE-1) for Leukopenia and Cancer-related Fatigue in Breast Cancer Patients With Radiotherapy

• Status: Completed
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: Female

Summary

Many breast cancer patients will taking Chinese herbal medicine during receiving radiotherapy. The investigators conducted the pilot study showing Compound Herbal Formula (TPE-1) have the effect of improving the fatigue and leukopenia during radiotherapy. So the investigators designed this double blind and controlled trial to evaluate whether TPE-1 have the effects for leukopenia and cancer-related fatigue in breast cancer patients with radiotherapy. From our initial observation for 2 years, TPE-1 is safety. The study is also designed to evaluate the safety when patients taking this formula.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Taipei City Hospital
• Collaborator: Taipei Medical University Shuang Ho Hospital

Criteria

Inclusion Criteria:

• breast cancer

• age between 18 to 70 yrs

• finished chemotherapy (adriamycin ), will receiving radiotherapy

• Chinese population

• KP$ between 40-100

• ECOG < 2

• WBC >4X10(9)／L and Hb > 10g/dl

• Assigned informed concent.

Exclusion Criteria:

• receiving operation during 14 days

• blood transfusion during one month.

• ALT >100mg/dL

• Creatinine >2.0mg/dL

• Total bilirubin >2.0mg/dL

• Infection

• prolation

• Taking anti-seizure , psychological drugs or any drugs not suitable patients

• AIDS or any disease diagnosed by physician and not suitable patients.