Comprehensive Treatment for Different Types of Tumor Thrombi in the Portal Vein for Hepatocellular Carcinoma Patients

• Status: Completed
• Trial end date: 2010-12-01
• Target enrollment: 0
• Participant gender: All

Summary

This study is working to evaluate the surgical comprehensive treatment for different types of tumor thrombi in the portal vein for hepatocellular carcinoma patients, to establish a standardized, unified, effective therapeutic program.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Eastern Hepatobiliary Surgery Hospital
• Treatments: Endostar protein; Fluorouracil

Criteria

Inclusion Criteria:

• Male or female patients > 30 years and <=60 years of age.

• with a clinical diagnosis of primary liver cancer with PVTT, without any adjuvant therapy.

• resectable tumors in the liver.

• PVTT type for II or III (based on the PVTT type system established by our groups), confirmed through pre-operative imaging and pathologic examination.

• liver function grade A or B of the Child-Pugh classification.

• No dysfunction in major organs; Blood routine, kidney function, cardiac function and lung function are basically normal. Hb ≥95g/L,WBC ≥3.000 cells/mm³,platelets ≥80.000 cells/mm³.

• Patients who can understand this trial and have signed information consent.

Exclusion Criteria:

• have had an allergic reaction following iodine or chemotherapeutic drugs.

• with extrahepatic metastasis.

• Patients with apparent cardiac, pulmonary, cerebral and renal dysfunction,which may affect the treatment of liver cancer.

• liver function:Child C.