Computerized Exercise Training for Cognitive Remediation in Adults With Multiple Sclerosis Treated With Gilenya

• Status: Completed
• Trial end date: 2015-09-01
• Target enrollment: 0
• Participant gender: All

Summary

This study is investigating the efficacy of computer-based cognitive exercises as a means of cognitive remediation in patients with Multiple Sclerosis (MS) who are beginning the disease modifying pharmacotherapy Gileyna.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Stony Brook University
• Collaborator: Novartis
• Treatments: Fingolimod Hydrochloride

Criteria

Inclusion Criteria:

• Ages 18-70

• Relapsing Remitting MS Diagnosis [81]

• Initiating Gilenya therapy, or current Gilenya therapy (kept constant for the past one month)

• No relapse or steroids in previous month

• Reading score on WRAT-3 of 37 or greater

• Visual, auditory and motor capacity to operate computer software, as judged by treating neurologist or study staff.

Exclusion Criteria:

• Previous trial of Gilenya therapy

• History of mental retardation, pervasive developmental disorder or other neurological condition associated with cognitive impairment

• Primary psychiatric disorder or unstable medical disorder that would influence ability to participate

• History of computer-based training with procedures similar to those proposed

• Learned English language after 12 years of age

• Unable to comply with study procedures