Overview

Concurrent Chemoradiotherapy(CRT) in Locally Advanced(LA) SCCHN vs Cetuximab With Radiotherapy (RT) After Neoadjuvant Chemotherapy

Status:
Unknown status

Trial end date:
2018-09-01

Target enrollment:

Participant gender:

Summary

Verify the effect and the incidence of oral mucositis of concurrent chemoradiotherapy in locally advanced squamous cell carcinoma of the head and neck versus concomitant cetuximab with radiotherapy after neoadjuvant chemotherapy. The predictive effect of Apurinic/apyrimidinic endonuclease 1(APE1)/ Ref-1 protein and Apurinic/apyrimidinic endonuclease 1(APE1)/Ref-1 antibody on oral mucositis.

Phase:

Phase 2

Details

Lead Sponsor:

Daping Hospital and the Research Institute of Surgery of the Third Military Medical University

Treatments:

Cetuximab
Docetaxel