Continuous Bupivacaine Infusion Following Colonic Surgery

• Status: Withdrawn
• Trial end date: 2009-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The primary objective is to evaluate the influence of continuous local anesthetic infiltration on tissue oxygenation after surgical procedures requiring abdominal surgery as a major predictor for wound healing.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The Cleveland Clinic
• Treatments: Bupivacaine

Criteria

Inclusion Criteria:

1. 18-80 years of age.

2. The patient has provided written informed consent.

3. The patient is scheduled for abdominal surgery.

4. The patient has an ASA of I, II, or III.

5. The patient understands the explanation of the protocol.

Exclusion Criteria:

1. Patients aged < 18 and > 80 years.

2. History of diabetes mellitus.

3. History of congestive heart failure.

4. History of peripheral vascular disease.

5. History of smoking.

6. History of Dysautonomia.

7. History of thyroid disease.

8. Susceptibility to malignant hyperthermia.

9. History of morbid obesity.

10. History of fever

11. History of infection.

12. Contraindication to the placement of an arterial line; e.g., Raynaud's disease.

13. The patient declines participation.

14. Any patient the investigator feels is not a candidate for this study.

15. Any patient with a history of known alcohol, analgesic, or narcotic substance abuse within two years of screening.