Continuous Lidocaine Infusion Via Closed Chest Drainage Tube for Pain Control After Thoracoscopic Partial Lung Resection

• Status: Not yet recruiting
• Trial end date: 2023-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The goal of this clinical trial is to learn about the effects on postoperative analgesia of continuous lidocaine infusion via closed chest drainage tube for patients undergoing thoracoscopic partial lung resection. The main questions it aims to answer are:

• To explore whether continuous lidocaine pumping via closed chest drainage tube has good analgesic and anti-inflammatory effects for patients undergoing partial thoracoscopic pneumonectomy.

• Whether the multimodal analgesia combined with continuous lidocaine pump can reduce the postoperative application of opioids, reduce the occurrence of postoperative complications, and promote the recovery of postoperative lung function and accelerate recovery.

For participants who undergoing the thoracoscopic partial lung resection with postoperative indwelling drainage tube, the epidural tube fixed in the drainage tube is connected to the completed infusion pump (marking the chest drain for analgesia). The comparison group only accept the intravenous analgesia after surgery.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Qilu Hospital of Shandong University
• Treatments: Lidocaine

Criteria

Inclusion Criteria:

1. participants ages 18-70 years.

2. participants undergoing thoracoscopic partial lung resection with an indwelling drainage tube after surgery.

3. American Society of Anesthesiologists classification (ASA)I-III.

Exclusion Criteria:

1. severe heart failure, cardiac arrhythmias,the New York Heart Association(NYHA) classification≥III.

2. hypersensitivity to lidocaine,History of local anesthetic poisoning.

3. severe renal or hepatic dysfunction.

4. body mass index (BMI)>35 kg m-2.

5. severe pleural adhesions.