Continuous Sciatic Nerve Block vs Epidural Analgesia in Lower Limb Amputation for Postoperative Pain

• Status: Not yet recruiting
• Trial end date: 2025-07-01
• Target enrollment: 0
• Participant gender: All

Summary

Controlled clinical trial of two parallel groups, with random assignment 1:1, non-inferiority, blinded for the patient, for who administers the intervention and for who analyzes the data. 112 participants

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Universidad de Antioquia

Criteria

Inclusion Criteria:

1. Age over 18 years

2. Being scheduled for above or below knee amputation or for bone remodeling of lower limb amputees

3. Acceptance of continuous regional analgesic technique as part of their multimodal analgesia

Exclusion Criteria:

1. Traumatic cause of amputation

2. Allergy to local anesthetics

3. Contraindication for epidural technique or continuous blocks

4. Stage 5 kidney disease

5. Concomitant use of aspirin and clopidogrel

6. Pregnancy status