Overview

Continuous vs Intermittent Ketorolac for Pain Control in Peds CV Surgery

Status:
Not yet recruiting

Trial end date:
2021-12-01

Target enrollment:
0

Participant gender:
All

Summary

The proposed study will be a prospective, randomized, double blind, placebo controlled trial to compare the use of a continuous infusion versus intermittent ketorolac on postoperative patients in the pediatric cardiovascular ICU. We intend to determine if the continuous infusion leads to a decreased utilization of opiates when compared to intermittent ketorolac.

Phase:

Phase 4

Accepts Healthy Volunteers?

Details

Lead Sponsor:

Phoenix Children's Hospital

Treatments:

Ketorolac
Ketorolac Tromethamine

Criteria

Inclusion Criteria:

1. All patients aged 3 months to 4 years admitted post operatively to the CVICU during
the 12 month time period during which the study will be ongoing

2. Initiation of study medication within the first 48 hours post-operatively

Exclusion Criteria:

1. Patients that have acute kidney injury, as defined by pRIFLE criteria.

2. History of allergy or sensitivity reaction to ketorolac or any NSAID medications.

3. Requiring mechanical circulatory support (ECMO) or continuous renal replacement
therapy (CRRT) within the first 48 hours post-operatively

4. Orthotopic heart transplantation

5. Clinically significant bleeding