Contrast Enhanced Ultrasound Evaluation of Brain Perfusion in Neonatal Post-Hemorrhagic Hydrocephalus

• Status: Withdrawn
• Trial end date: 2018-01-22
• Target enrollment: 0
• Participant gender: All

Summary

The aim of the proposed project is therefore to utilize the CEUS technique to assess cerebral perfusion changes before and after ventricular shunting in neonatal cases of PHH. The expectation of the proposed project is to validate statistically significant cerebral perfusion differences before and after shunting in neonates with PHH, as a preliminary feasibility study prior to conducting a large scale, prospective clinical trial incorporating therapeutic interventions using the CEUS technique.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Johns Hopkins University

Criteria

Inclusion Criteria:

• Preexisting IV line

• Stable clinical condition

• No prior allergy to ultrasound contrast agents

• Presence of post-hemorrhagic hydrocephalus

Exclusion Criteria:

• Unstable clinical condition

• Inability to complete the exam

• Allergy to ultrasound contrast agents