Contrast Enhanced Ultrasound and Shear Wave Elastography in Measuring Response in Patients With Breast Cancer Receiving Chemotherapy Before Surgery

• Status: Terminated
• Trial end date: 2016-09-25
• Target enrollment: 0
• Participant gender: Female

Summary

This pilot clinical trial studies contrast enhanced ultrasound and shear wave elastography in measuring response in patients with breast cancer receiving chemotherapy before surgery. New imaging procedures, such as contrast enhanced ultrasound and shear wave elastography, may predict treatment response earlier and more accurately than contrast enhanced magnetic resonance imaging.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Southern California
• Collaborators: L K Whittier Foundation; National Cancer Institute (NCI)

Criteria

Inclusion Criteria:

• Women with histologically confirmed breast cancer (by core needle biopsy)

• Women with >= 2 cm clinically or radiologically measureable breast cancer

• Women scheduled to receive neoadjuvant chemotherapy as part of their treatment plan

• Women competent to sign study specific written Informed Consent

• Women willing to comply with protocol requirements

Exclusion Criteria:

• Women who are pregnant

• Women who have undergone open surgical (excisional) biopsy for breast cancer diagnosis

• Women who have had a prior history of breast cancer in the same breast

• Women with known cardiac shunt, pulmonary hypertension or hypersensitivity to perflutren agent

• Women who cannot consent for themselves