Contrast Enhanced Ultrasound for Evaluation of Reflux Nephropathy

• Status: Completed
• Trial end date: 2016-11-01
• Target enrollment: 0
• Participant gender: All

Summary

The study will be evaluating the efficacy and safety of a contrast drug in pediatric renal ultrasound.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Tennessee

Criteria

Inclusion Criteria:

• Informed consent

• Age more than or equal to 8 years

• Patient with history of urinary tract infection (UTI) and history of Voiding Cystourethrogram (VCUG) for vesicoureteral reflux

• Candidate for Dimercaptosuccinic acid (DMSA) scan or scan for renal scar

• Demonstration of renal scarring by DMSA scan or renal ultrasound without contrast

Includes healthy volunteers

Exclusion Criteria:

• Age less than 8years

• Allergy to contrast or related products

• Cardiac shunt/ congenital heart anomalies

• Abnormal baseline ECG

• Open heart surgery

• Evidence of retinopathy

• Patient in intensive care

• Unable to comply with study requirement

• History of emphysema

• Unable to maintain oxygen saturation of 92% on at room air

• Pregnancy and lactation