Contrast-enhanced Ultrasound (CE-US) and Magnetic Resonance Imaging (MRI): Evaluating Plaque Neovascularisation
Status:
Completed
Trial end date:
2010-04-01
Target enrollment:
Participant gender:
Summary
The first goal of this study is to investigate whether CE-US is able to accurately identify
and quantify neovascularisation in carotid artery plaques. Since this is one of the first
studies systematically evaluating the ability of ultrasound in combination with air bubbles
to evaluate neovascularisation in carotid artery plaques, the examination will be performed
twice with an interval of 1/2 hour on the day before surgery, thus studying the reliability
of the method.
The second goal of this study is to investigate whether MRI at 3.0 T with a custom-designed
3T carotid coil, using a recently developed pulse sequence, is able to accurately identify
and quantify neovascularisation. And the third goal of this study is to make an intermodality
comparison of CE-US and MRI regarding their ability to identify and quantify plaque
neovascularisation.