Contrast-enhanced Ultrasound Versus CT Scan for Kidney Stone Patient Management
Status:
Not yet recruiting
Trial end date:
2022-12-30
Target enrollment:
Participant gender:
Summary
This study will be a randomized controlled study comparing the use of two clinical management
strategies in nephrostomy tube management following percutaneous nephrolithotomy (PCNL). The
first strategy entails using contrast-enhanced ultrasound (CEUS) to evaluate the renal
collecting system (1). This is a new imaging approach applying ultrasound machines with
special software in combination with intraluminal ultrasound contrast agent (Lumason)
injection, which is an FDA-approved ultrasound contrast agent (2). The second strategy is a
nephrostomy tube capping trial combined with low dose non-contrast computed tomography (CT)
scan, one of the most frequently utilized clinical management strategies currently used in
clinical practice (3).
Phase:
Phase 2
Details
Lead Sponsor:
University of California, San Francisco
Collaborators:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Oregon Health and Science University