Overview

Contribution of Hyperinsulinemia vs. Hyperglycemia to Insulin Resistance in Type 1 Diabetes and Maturity Onset Diabetes of the Young, Type 2 (MODY2)

Status:
Completed

Trial end date:
2019-02-01

Target enrollment:

Participant gender:

Summary

The purpose of this study is to determine the key factors influencing insulin sensitivity in type 1 diabetes (T1DM) and maturity onset diabetes of the young, type 2 (MODY2). Our study tests the hypothesis that decreased insulin sensitivity is primarily driven by chronically elevated insulin levels in the blood rather than chronic elevations in blood sugar.

Phase:

Phase 1

Details

Lead Sponsor:

Vanderbilt University
Vanderbilt University Medical Center

Treatments:

Benzocaine
Glucagon
Hormones
Insulin
Insulin, Globin Zinc
Somatostatin