Control of Cognition (Naltrexone, Methylphenidate, and ADHD Study (NMAS))
Status:
Completed
Trial end date:
2017-02-01
Target enrollment:
Participant gender:
Summary
The goal of this research is to understand the functioning of 'regulatory circuits' in the
brain. We are also interested in how the medications methylphenidate and naltrexone affect
these regulatory circuits. This research study will use a scanning technique known as
functional magnetic resonance imaging (fMRI) which takes a special kind of picture of the
brain that enables us to "see the brain at work". Adult participants will be given a one-time
dose of either methylphenidate, naltrexone,or placebo before each fMRI scan session.
The main purpose for this research is to better understand the functioning of regulatory
circuits in healthy individuals and individuals with psychiatric disorders. This research may
one day help us develop better treatments for these disorders.