Control of Periodontal Infections

• Status: Completed
• Trial end date: 2004-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to test combined effects of scaling and root planing with periodontal surgery, systemically administered amoxicillin and metronidazole, and/or local tetracycline on pocket depth reduction and attachment level "gain" in patients with chronic periodontitis.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The Forsyth Institute
• Collaborators: Boston University; Göteborg University
• Treatments: Amoxicillin; Anti-Bacterial Agents; Antibiotics, Antitubercular; Metronidazole; Tetracycline

Criteria

Inclusion Criteria:

• greater than 20 years of age

• had a least 15 natural teeth

• in good general health

• at least 4 teeth with pockets > 6 mm

• at least 8 teeth with AL > 3 mm at baseline

Exclusion Criteria:

• pregnant or nursing (if female)

• having antibiotic or periodontal therapy in the previous three months

• systemic conditions that would affect the course of periodontal disease

• systemic conditions that required antibiotic coverage

• allergic to drugs used in the study