Controlled Hyperventilation as Prophylaxis for Acute Mountain Sickness

• Status: Unknown status
• Trial end date: 2017-05-01
• Target enrollment: 0
• Participant gender: All

Summary

This study evaluates the safety and efficacy of the voluntary ventilatory response as prophylaxis for acute mountain sickness, measured by the Lake Louise Self-Report Score, comparing to a group using acetazolamide.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Hospital del Trabajador de Santiago
• Treatments: Acetazolamide

Criteria

Inclusion Criteria:

• Living at lower altitude than 900 meters

Exclusion Criteria:

• Cardiac or pulmonary comorbidity

• Smoking

• Infectious disease during the last 30 days

• BMI> 30

• Pharmaceutical use as diuretics, corticosteroids, acetazolamide, or anti -inflammatory drugs during the 2 weeks prior to the study

• A history of high altitude cerebral edema or high altitude pulmonary edema

• Cardiovascular risk factors such as a personal history of cardiovascular disease, familial history of major adverse cardiovascular events (MACE) at age younger than 45 yrs, hypercholesterolemia and stroke.