Controlled Ovarian Stimulation Followed by Timed Intercourse or Intrauterine Insemination in Infertile PCOS Patients
Status:
Suspended
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
At the present the first options to induce ovulation in polycystic ovary syndrome with
anovulatory infertility are clomiphene citrate (CC) and metformin. Notwithstanding the
effectiveness of CC and metformin alone or in a sequential or combined regimen, a percentage
of patients ranging from 5% to 30% remain anovulatory. For these patients, the use of
gonadotropins for controlled ovarian stimulation (COS) is indicated.
Moreover, to date it isn't clear if COS should be followed by timed intercourse (TI) or
intrauterine insemination (IUI).
The aim of the present study will be to compare TI and IUI in infertile PCOS patients
undergoing COS in terms of cost-benefit.