Controlled Study of the Ability of a Smokefree Tobacco Product to Increase the Quit Rate Among Cigarette Smokers

• Status: Completed
• Trial end date: 2010-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The study aims to assess if use of a low-nitrosamine, Swedish, smokefree tobacco product for oral use ("snus") can increase the quit rate among cigarette smokers who wish to stop smoking

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Swedish Match AB
• Treatments: Lobeline

Criteria

Inclusion Criteria:

• Cigarette smoker who smoke more than 9 cigarettes per day (average during past month)

• Daily smoking more than 1 year

• Motivated to quit smoking using a smokefree tobacco product

• Good general health

Exclusion Criteria:

• Use of smokefree/smokeless tobacco during past 6 months or any type of pharmaceutical product for smoking cessation during past 3 months

• Unable to refrain from nicotine replacement therapy during the study

• Current oral condition that could be made worse by study interventions

• History of clinically significant renal, hepatic, neurological, or chronic pulmonary disease that in the judgement of the investigator might preclude participation

• History of significant cardiovascular disease, including myocardial infarction, within the last 3 months, significant cardiac arrythmias, or poorly controlled hypertension that in the judgement of the investigator might preclude participation

• History of alcohol or substance abuse other than cigarette smoking within the past year