Cooperative Group for Clinical Research in G-POEM (POP), Jiangsu, China

• Status: Unknown status
• Trial end date: 2019-12-16
• Target enrollment: 0
• Participant gender: All

Summary

Diabetic gastroparesis, postsurgical gastroparesis, idiopathic gastroparesis and primary pyloric stenosis are debilitating gastrointestinal motility disorder. However, there is limited medical therapeutic options for these diseases. Gastric peroral endoscopic pyloromyotomy (G-POEM) is an emerging novel endoscopic technique which is reported as a minimally invasive therapy. But so far, the efficacy and safety of G-POEM on these diseases are rarely explored. So, there is a cooperative group composed of five clinical centers for clinical research in G-POEM.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Zhongda Hospital
• Treatments: Citric Acid; Esomeprazole; Mosapride

Criteria

Inclusion Criteria:

1. Age between 16 to 80 years old

2. Full sufficiency in literacy

3. Be off proton pump inhibitor, antacids and prokinetics ≥ 2 weeks

4. Refractory gastroesophageal reflux disease induced by postsurgical gastroparesis

Exclusion Criteria:

1. Severe heart, lung, and cerebrovascular disease

2. Severe hematopoietic system disease

3. Abnormal blood coagulation function

4. Oropharyngeal abnormalities

5. Severe spine malformation

6. In pregnancy and lactation at present, or plan to become pregnant within 2 years

7. Severe inflammation or huge ulcers in stomach

8. Mental and psychological disorder