Corneal Collagen Cross-linking for Progressive Keratoconus

• Status: Completed
• Trial end date: 2011-04-01
• Target enrollment: 0
• Participant gender: All

Summary

Prospective, randomized multicenter study to determine the safety and effectiveness of performing cornea collagen cross-linking (CXL) using riboflavin and UVA light in eyes with progressive keratoconus.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Avedro, Inc.; Glaukos Corporation
• Treatments: Ophthalmic Solutions; Pharmaceutical Solutions; Riboflavin

Criteria

Inclusion Criteria:

• Diagnosis of keratoconus

• Documented progression over previous 24 months

• Decreased BSCVA

• Must complete all study visits

Exclusion Criteria:

• Prior corneal surgery or Intacs

• History of delayed wound healing