Corneal Tear Film Imaging of the Cornea Before and After Restasis Therapy
Status:
Unknown status
Trial end date:
2018-12-30
Target enrollment:
Participant gender:
Summary
Dry Eye Syndrome (DES) is a disease affects the production and stability of the tear film,
leading to vision disturbances and a major decrease in quality of life. The most recommended
treatment for moderate-severe DES today which failed conservative therapy with lubricating
eye drops is topical Cyclosporine 0.05% (Restasis®).
The Tear Film Imager (TFI) is a novel imaging modality designed for visualization of the
individual tear film layers up to a resolution of 0.1 micrometers, a property not enabled by
any other imaging modality for this indication to date.
In this study we wish to assess the effects of topical Cyclosporine 0.05% on the tear film
using the TFI. In our previous study we found this modality yields high resolution images of
the tear film, yielding significant differences between healthy and diseased (DES) eyes. We
believe the TFI will improve quality of assessment and follow-up of DES patients, allowing
more effective diagnosis and treatment of this disease in the future.