Coronary Bypass and Artotic Leaflet Surgery : Heparin Low Dose vs Full Dose

• Status: Completed
• Trial end date: 2013-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to demonstrate superiority on postoperative bleeding from the use of a heparin half dose compared to a conventional dose, under mini-extra corporeal circulation, without increased risk to the patient.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital, Bordeaux
• Treatments: Calcium heparin; Heparin

Criteria

Inclusion Criteria:

• single or multiple coronary bypass

• written and informed consent

• repair or replacement of artic leaflet

• platelet suppressive agents stopped since at least 7 days

• anticoagulants stopped since at least 3 days

Exclusion Criteria:

• Thoracic surgery antecedent

• ASA 4

• carotid stenosis > 75%

• Hb < 10,5 g/l

• chronic hepatic failure

• thromboembolic antecedent