Correlation Between Acute Analgesia and Long-Term Function Following Ankle Injuries

• Status: Unknown status
• Trial end date: 2019-12-01
• Target enrollment: 0
• Participant gender: All

Summary

In this 4-arm pragmatic randomized control trial, the investigators hope to decipher whether the use of non-opioid analgesics (naproxen, celecoxib, acetaminophen) in addition to standardized physiotherapy during the acute phase of grade I-II ankle injuries will result in functional differences compared to standardized physiotherapy alone

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Canadian Department of National Defense
• Treatments: Acetaminophen; Celecoxib; Naproxen

Criteria

Inclusion Criteria:

• Acquired acute ankle injury (injured less than 48 hours ago);

• Clinical diagnosis of a Grade I or II ankle sprain

• Is eligible to receive comprehensive medical care from Garrison Petawawa

Exclusion Criteria:

• Diagnosis of ankle fracture or ligament rupture

• Has planned release from the Canadian Armed Forces within one year;

• Documented restrictions on military duties

• Has known intolerance or documented adverse reaction to acetaminophen or naproxen or celecoxib

• Documented history of liver or kidney problems

• pregnant or breastfeeding