Cortical Modulation of Acute Post-thoracotomy Pain With Transcranial Direct Current Stimulation

• Status: Completed
• Trial end date: 2018-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The primary objective of this single center, prospective, randomized, double blind clinical trial is to evaluate the effectiveness of anodal transcranial direct current stimulation (tDCS) combined with patient controlled analgesia (PCA) morphine, on intravenous morphine use for postoperative analgesia after thoracotomy. The intervention group will receive treatment with anodal tDCS, whereas the control group will receive sham stimulation.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Military Medical Academy, Belgrade, Serbia
• Treatments: Morphine

Criteria

Inclusion Criteria:

• Subject is willing and able to provide written informed consent,

• Subject is 18-80 years old,

• Subject needs thoracotomy for confirmed malignant lung disease,

• Subject is extubated in the operating room

Exclusion Criteria:

• Subject is pregnant

• Subject is in treatment for psychiatric disease

• Subject is in treatment for neurological disease

• Subject is in treatment for chronic pain

• Subject has history of current or past alcohol or Street Drug abuse

• Subject has received chemotherapy

• Subject has history of previous thoracic or cardiac surgery

• Subject is allergic to medications that will be used in the study

• Subject has pacemaker or automatic implantable cardioverter/defibrillator

• Subject has implants or any other devices in the head, the spinal cord or peripheral nerves

• Subject has confirmed brain lesion, including tumor or metastasis