Corticosteroid Prophylaxis on the Cardiopulmonary Bypass-Induced Systemic Inflammatory Response

• Status: Completed
• Trial end date: 2011-08-01
• Target enrollment: 0
• Participant gender: All

Summary

To observe the effect of glucocorticoid on the dynamic changes of monocyte subsets in the peripheral blood of valve disease patients undergoing cardiopulmonary bypass perioperatively.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Beijing Anzhen Hospital; Capital Medical University
• Collaborator: National Natural Science Foundation of China
• Treatments: Methylprednisolone; Methylprednisolone Hemisuccinate

Criteria

Inclusion Criteria:

• Valve replacement under cardiopulmonary bypass

Exclusion Criteria:

• Cardiopulmonary bypass time over 120 minutes

• Hyperlipidemia

• Diabetes mellitus

• Autoimmune diseases