Overview

Cortisol Augmentation of Prolonged Exposure Therapy

Status:
Completed
Trial end date:
2011-02-01
Target enrollment:
Participant gender:
Summary
This study seeks to examine the efficacy of hydrocortisone administration in the augmentation of the therapeutic effects of Prolonged Exposure (PE) therapy, an empirically tested treatment shown to be effective in the the treatment of posttraumatic stress disorder (PTSD). The augmentation builds on both the translation of neuroscience findings demonstrating the effects of glucocorticoids (GCs) on learning, and on empirical clinical findings from other investigators demonstrating beneficial effects of GCs in reducing traumatic memories in trauma-exposed persons.
Phase:
N/A
Details
Lead Sponsor:
VISN 3 Mental Illness Research, Education and Clinical Center
Treatments:
Cortisol succinate
Hydrocortisone
Hydrocortisone 17-butyrate 21-propionate
Hydrocortisone acetate