Creatine Treatment for Female Adolescents With Depression Who Are Non-Responders to Fluoxetine or Escitalopram
Status:
Completed
Trial end date:
2012-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to see if creatine, which is a naturally occurring chemical in
the body, is effective for treating Major Depressive Disorder (MDD) in female teenagers.
Creatine may have effects of interest in the brain. The reason for the MRI component of this
study is to learn about new ways to see inside the brain. The investigators will use magnetic
fields and radio waves to look at the brain and chemicals in the brain. The investigators
hope that this technique will have medial use in the future.
The primary hypothesis of the study is that oral creatine supplementation will have a
beneficial effect as adjunctive therapy in female adolescents with MDD who are non-responders
to an adequate trial of the SSRIs Fluoxetine or Escitalopram.