Overview

Cryptococcal Optimal ART Timing Trial

Status:
Completed
Trial end date:
2013-03-01
Target enrollment:
Participant gender:
Summary
The Cryptococcal Optimal ART Timing (COAT) trial seeks to determine after cryptococcal meningitis (CM) whether early initiation of antiretroviral therapy (ART) prior to hospital discharge results in superior survival compared to standard initiation of ART started as an outpatient.
Phase:
Phase 4
Details
Lead Sponsor:
University of Minnesota
University of Minnesota - Clinical and Translational Science Institute
Collaborators:
Makerere University
Mbarara University of Science and Technology
National Institute of Allergy and Infectious Diseases (NIAID)
University of Cape Town
Treatments:
Efavirenz
Lamivudine
Stavudine
Zidovudine