Crystalloid Fluid Choice and Neurological Outcome in Patients After Subarachnoid Haemorrhage

• Status: Not yet recruiting
• Trial end date: 2023-06-01
• Target enrollment: 0
• Participant gender: All

Summary

Patients with subarachnoid hemorrhage are prone to suffer from dysnatriemia. Evidence shows that hyponatriemia is associated with increased incidence of vasospasm, brain swelling and mortality in these patients. Patients with subarachnoid hemorrhage often require large amounts of iv fluids in order to maintain euvolemia and support cardiocirculatory function. Prior evidence shows that the type of infusion fluid significantly influences blood sodium content. Hence, this study evaluated whether the sodium content of the infusion solution impacts mortality and morbidity in patients with subarachnoid hemorrhage.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital Inselspital, Berne

Criteria

Inclusion Criteria:

All adult patients suffering from non-traumatic subarachnoid haemorrhage.

Exclusion Criteria:

• Patients with major intra-cranial trauma

• Diagnosis of an AV-malformation as the source of subarachnoid hemorrhage on the primary CT

• Patients who are transferred to the investigators' institution and arrive more than 24 hours after diagnosis of subarachnoid haemorrhage as diagnosed by CT scan

• Patients with clear limitation to therapy at hospital admission (eg ICU admission for evaluation of organ donation)

• Declining of informed consent