Culturally Adapted Mobile Treatment of Chronic Pain in Adolescent Survivors of Pediatric Bone Sarcoma

• Status: Recruiting
• Trial end date: 2025-10-01
• Target enrollment: 0
• Participant gender: All

Summary

This is a prospective study that will conduct a series of focus groups with non-Hispanic Black and Hispanic childhood cancer survivors to obtain their input on culturally adapting a mobile CBT program for chronic pain and tDCS procedures. Once this adaptation process is completed, the investigators will conduct a feasibility trial with non-Hispanic Black, Hispanic and non-Hispanic White childhood cancer survivors of bone sarcoma with chronic pain. The feasibility study will assign eligible participants to either culturally adapted mobile CBT + active tDCS to the dorsolateral prefrontal cortex or culturally adapted mobile CBT + sham tDCS. We anticipate approximately 60 participants for the focus groups and approximately 30 participants for the feasibility study for a total of about 90 participants.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: St. Jude Children's Research Hospital
• Collaborator: National Institutes of Health (NIH)

Criteria

Inclusion Criteria for focus groups

• Adults

• Hispanic or non-Hispanic Black childhood cancer survivor or parent of Hispanic or non-Hispanic childhood cancer survivor

• 18 years or older

• Adolescents

• 10-17 year-old survivors of childhood cancer

• At least one year post treatment

• Hispanic or non- Hispanic Black

Exclusion Criteria for focus groups

• Adults/Adolescents

o Inability or unwillingness of research participant or legal guardian/representative to give written informed consent.

Inclusion Criteria for feasibility study

• Hispanic, non-Hispanic Black and non-Hispanic White 10-17 year old survivors of bone sarcoma

• At least one year post treatment

• Pain present over the past 3 months and pain at least once per week

• Pain interfering with at least one area of daily functioning

Exclusion Criteria for feasibility study

• Limb amputation

• History of seizures or other neurological disorders

• Implanted medical device or metal in the head

• Serious comorbid psychiatric condition

• Current substance abuse

• History of development delay or significant cognitive impairment