Cyclophosphamide and Celecoxib in Treating Patients With Advanced Cancer
Status:
Completed
Trial end date:
2012-02-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as cyclophosphamide, work in different ways to
stop the growth of cancer cells, either by killing the cells or by stopping them from
dividing. Celecoxib may stop the growth of cancer cells by blocking some of the enzymes
needed for cell growth. Giving cyclophosphamide together with celecoxib may help kill more
cancer cells.
PURPOSE: This phase I trial is studying the side effects and best dose of celecoxib when
given together with cyclophosphamide in treating patients with advanced cancer.