Cyclophosphamide and Paclitaxel With or Without Trastuzumab in Stage I-II Breast Cancer Who Have Undergone Surgery
Status:
Completed
Trial end date:
2015-09-28
Target enrollment:
Participant gender:
Summary
This phase II trial studies the side effects and how well giving cyclophosphamide and
paclitaxel with or without trastuzumab works in treating patients with stage I-II breast
cancer who have undergone surgery. Drugs used in chemotherapy, such as cyclophosphamide and
paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the
cells or by stopping them from dividing. Giving monoclonal antibody therapy, such as
trastuzumab, with chemotherapy may kill more tumor cells. Giving these treatments after
surgery may kill any tumor cells that remain after surgery.