Cyclophosphamide and Pulse Dexamethasone With Rapamycin or Hydroxychloroquine
Status:
Completed
Trial end date:
2012-10-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine the feasibility of giving (i) rapamycin or (ii)
hydroxychloroquine (HCQ), with standard doses of infusional cyclophosphamide and pulse
dexamethasone (cy/dex) for patients with relapsed/refractory multiple myeloma, as well as the
feasibility of obtaining multiple blood and bone marrow samples during treatment to assess
the pharmacodynamic effects of the treatment.
Phase:
Early Phase 1
Details
Lead Sponsor:
Abramson Cancer Center of the University of Pennsylvania