Cyclosporine A C-2h Monitoring Versus Tacrolimus C-0h Monitoring in de Novo Liver Transplant Recipients
Status:
Completed
Trial end date:
2007-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine whether cyclosporine A (in a micro emulsion
formulation) monitored by sample taken 2 hour after oral dose (C-2h) will show equivalent or
superior efficacy compared to tacrolimus monitored by pre-dose blood concentration (C-0h). In
addition this study will assess the safety and tolerability of a cyclosporine A regimen based
on C-2h monitoring in comparison to the standard tacrolimus regimen.