Overview

Cyclosporine For The Treatment Of COVID-19(+)

Status:
Recruiting
Trial end date:
2025-11-23
Target enrollment:
Participant gender:
Summary
Phase IIa clinical trial in which 75 non-ICU hospital inpatients will be randomized 2:1 to 7 days of an oral formulation of cyclosporine, Neoral (2.5mg/kg PO BID) + standard of care (SOC) or no Neoral + SOC. The primary endpoint is disease severity based on the World Health Organization (WHO) COVID Ordinal Outcomes Scale, on day 14. Secondary endpoints include safety and changes in serum inflammatory markers.
Phase:
Phase 2
Details
Lead Sponsor:
Bryan Burt, MD
Collaborator:
Brigham and Women's Hospital
Treatments:
Cyclosporine
Cyclosporins