Cystic Breast Masses by Contrast Enhanced Ultrasound (CEUS)

• Status: Completed
• Trial end date: 2018-04-29
• Target enrollment: 0
• Participant gender: Female

Summary

The overarching goal of the proposed research is to evaluate whether qualitative and quantitative parameters in real time contrast enhanced ultrasound (CEUS) can aid in assessing suspicious indeterminate cystic appearing breast masses and ultimately determine whether or not an ultrasound guided biopsy is necessary. The underlying hypothesis is that breast masses (given BIRADS 4) that lack enhancement on CEUS will have a benign histology obtained by ultrasound guided core biopsy and/or surgery. Then, in the future, these non-enhancing cystic lesions can be followed and do not need biopsy intervention.

• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Southern California
• Collaborator: Wright Foundation

Criteria

Inclusion Criteria:

• >18 years of age

• recommended for an ultrasound guided biopsy due to breast mass detection

Exclusion Criteria:

• < 18 years of age

• prior history of breast cancer

• prior history of biopsy for that specific lesion

• any condition that would be a contraindication to the microbubble contrast agent used in CEUS such as pulmonary hypertension, 3cardiac shunts, and allergy to perflutren.