Cytotoxicity of Yellow Fever Specific CD8 T Cells Following YF-17D Vaccination

• Status: Active, not recruiting
• Trial end date: 2022-02-15
• Target enrollment: 0
• Participant gender: All

Summary

Investigating cytotoxicity of yellow fever specific CD8 T cells following YF-17D vaccination and the following licensing of these epitope-specific CD8 T cells

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Aarhus
• Collaborator: Martin Tolstrup
• Treatments: Vaccines

Criteria

Inclusion Criteria:

• Age between 18 to 60 years

• Informed consent given

Exclusion Criteria:

• Fever (orally >37,5 C) on day of vaccination

• Immunosuppressants

• Pregnant or breast feeding

• Severe immunodeficiency

• Known thymus dysfunction

• Allergy against egg

• Known haemophilia

• Previous severe reaction to vaccine

• Not willing to use anticonceptives 4 weeks after vaccination