D-Cycloserine Augmentation of Cognitive Behavioral Therapy for Delusions
Status:
Completed
Trial end date:
2017-10-01
Target enrollment:
Participant gender:
Summary
This study is a placebo-controlled 12 week trial of DCS augmentation of once-weekly CBT
sessions in 60 schizophrenia subjects with antipsychotic-resistant delusions. In addition to
testing efficacy, this trial will characterize DCS effects in terms of time course and
persistence of response and will examine DCS effects on memory consolidation and cognitive
flexibility as possible mediators of DCS enhancement of CBT for delusions.
Phase:
Phase 4
Details
Lead Sponsor:
New York University School of Medicine NYU Langone Health